A xenobiotic (toxicant) may be absorbed into an animal via different routes. After absorption it is distributed to different parts of the body and, finally, is available for excretion. Many xenobiotics are known to undergo biotransformation while in the organs and tissues. Biotransformation is also termed metabolic transformation. Definition of Biotransformation: Biotransformation may be defined […]
Biotransformation of Toxicants in Animals | Toxicology
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Bioaccumulation of Xenobiotics in Animals | Toxicants | Toxicology
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In this article we will discuss about:- 1. Introduction to Bioaccumulation of Xenobiotics 2. Process of Bioaccumulation 3. Illustration of Biomagnification of Important Xenobiotics 4. Factors Affecting 5. Elimination 6. Important Cases. Introduction to Bioaccumulation of Xenobiotics: Bioaccumulation of xenobiotic compounds first gained public attention in the 1960s with the invention of DDT, DDD and methyl […]
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Toxicant Dose-Response Relationship | Toxicology
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In this article we will discuss about the toxicant dose-response relationship observed in animals. The term ‘dose’ is defined as the quantity of toxicant administered to, or received by, the animal at one time or in given period of time. ‘Dosage’ refers to the administration of toxicant in doses. The amount is readily ascertained when […]