In this article we will discuss about:- 1. Introduction to Xenobiotics 2. Concept of Membranous Barrier 3. Responses to Xenobiotics. Introduction to Xenobiotics: Xenobiotics are the environmental chemicals. It is a term derived from the Greek word — xenon = a stranger + bios = life i.e., stranger to life. The salient xenobiotics of concern to human health and environment are [...]
The biological system may be exposed to the high amounts/concentration of xenobiotics, but if the concentration at the specific sites remain low due to any reason viz., defensive mechanism, there appears little or no effect. In order to produce a measurable effect, a xenobiotic must be transported from the site of exposure to the specific sites of action. The process [...]
The following points highlight the thirteen main principal storage sites for xenobiotics in the living system. The storage sites are: 1. Plasma Proteins 2. Body Fat 3. Liver 4. Kidney 5. Bone 6. Brain and Nervous Tissues 7. Erythrocytes 8. Gonads 9. Respiratory Tract 10. G.I.T. 11. Gall Bladder 12. Spleen 13. Fetus. 1. Plasma Proteins as Storage Depot: Several [...]